Singh, H. W., Creamer, K. E., Chase, A. B., Klau, L. J., Podell, S., & Jensen, P. R. (2023). Metagenomic data reveals type I polyketide synthase distributions across biomes. MSystems, 8(3), e00012-23.
Chase, A. B., Bogdanov, A., Demko, A. M., & Jensen, P. R. (2023). Biogeographic patterns of biosynthetic potential and specialized metabolites in marine sediments. The ISME Journal, 17(7), 976–983.
Mascuch, S. J., Demko, A., Viulu, S., Ginigini, J., Soapi, K., Jensen, P., & Kubanek, J. (2022). Antibiotic activity altered by competitive interactions between two coral reef-associated bacteria. Microbial Ecology, 10.
Tuttle, R. N., Rouse, G. W., Castro-Falcon, G., Hughes, C. C., & Jensen, P. R. (2022). Specialized metabolite-mediated predation defense in the marine actinobacterium Salinispora. Applied and Environmental Microbiology, 88(1), 11.
Klau, L. J., Podell, S., Creamer, K. E., Demko, A. M., Singh, H. W., Allen, E. E., Moore, B. S., Ziemert, N., Letzel, A. C., & Jensen, P. R. (2022). The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function. Journal of Biological Chemistry, 298(10), 102480.
Castro-Falcon, G., Creamer, K. E., Chase, A. B., Kim, M. C., Sweeney, D., Glukhov, E., Fenical, W., & Jensen, P. R. (2022). Structure and candidate biosynthetic gene cluster of a manumycin-type metabolite from Salinispora pacifica. Journal of Natural Products, 85(4), 980–986. ://WOS:000791431400023
Chase, A. B., Sweeney, D., Muskat, M. N., Guillen-Matus, D. G., & Jensen, P. R. (2021). Vertical Inheritance Facilitates Interspecies Diversification in Biosynthetic Gene Clusters and Specialized Metabolites. Mbio, 12(6), 15.
Demko, A. M., Patin, N. V., & Jensen, P. R. (2021). Microbial diversity in tropical marine sediments assessed using culture-dependent and culture-independent techniques. Environmental Microbiology, 17.
Shang, Z., Ferris, Z. E., Sweeney, D., Chase, A. B., Yuan, C. H., Hui, Y., Hou, L. K., Older, E. A., Xue, D., Tang, X. Y., Zhang, W. P., Nagarkatti, P., Nagarkatti, M., Testerman, T. L., Jensen, P. R., & Li, J. (2021). Grincamycins P-T: Rearranged angucyclines from the marine sediment-derived Streptomyces sp. CNZ-748 inhibit cell lines of the rare cancer pseudomyxoma peritonei. Journal of Natural Products, 84(5), 1638–1648.
Schorn, M. A., Verhoeven, S., Ridder, L., Huber, F., Acharya, D. D., Aksenov, A. A., Aleti, G., Moghaddam, J. A., Aron, A. T., Aziz, S., Bauermeister, A., Bauman, K. D., Baunach, M., Beemelmanns, C., Beman, J. M., Berlanga-Clavero, M. V., Blacutt, A. A., Bode, H. B., Boullie, A., … van der Hooft, J. J. J. (2021). A community resource for paired genomic and metabolomic data mining. Nature Chemical Biology.
Kudo, Y., Awakawa, T., Du, Y. L., Jordan, P. A., Creamer, K. E., Jensen, P. R., Linington, R. G., Ryan, K. S., & Moore, B. S. (2020). Expansion of gamma-butyrolactone signaling molecule biosynthesis to phosphotriester natural products. Acs Chemical Biology, 15(12), 3253–3261.
Roman-Ponce, B., Millan-Aguinaga, N., Guillen-Matus, D., Chase, A. B., Ginigini, J. G. M., Soapi, K., Feussner, K. D., Jensen, P. R., & Trujillo, M. E. (2020). Six novel species of the obligate marine actinobacterium Salinispora, Salinispora cortesiana sp. nov., Salinispora fenicalii sp. nov., Salinispora goodfellowii sp. nov., Salinispora mooreana sp. nov., Salinispora oceanensis sp. nov. and Salinispora vitiensis sp. nov., and emended description of the genus Salinispora. International Journal of Systematic and Evolutionary Microbiology, 70(8), 4668–4682.
Nair, V., Kim, M. C., Golen, J. A., Rheingold, A. L., Castro, G. A., Jensen, P. R., & Fenical, W. (2020). Verrucosamide, a cytotoxic 1,4-thiazepane-containing thiodepsipeptide from a marine-derived actinomycete. Marine Drugs, 18(11).
Schlawis, C., Harig, T., Ehlers, S., Guillen-Matus, D. G., Creamer, K. E., Jensen, P. R., & Schulz, S. (2020). Extending the salinilactone family. Chembiochem, 21(11), 1629–1632.
Busch, J., Agarwal, V., Schorn, M., Machado, H., Moore, B. S., Rouse, G. W., Gram, L., & Jensen, P. R. (2019). Diversity and distribution of the bmp gene cluster and its Polybrominated products in the genus Pseudoalteromonas. Environmental Microbiology, 21(5), 1575–1585.
Tuttle, R. N., Demko, A. M., Patin, N. V., Kapono, C. A., Donia, M. S., Dorrestein, P., & Jensen, P. R. (2019). Detection of natural products and their producers in ocean sediments. Applied and Environmental Microbiology, 85(8).
Castro-Falcon, G., Millan-Aguinaga, N., Roullier, C., Jensen, P. R., & Hughes, C. C. (2018). Nitrosopyridine probe to detect polyketide natural products with conjugated alkenes: Discovery of novodaryamide and nocarditriene. Acs Chemical Biology, 13(11), 3097–3106.
Kim, M. C., Machado, H., Jang, K. H., Trzoss, L., Jensen, P. R., & Fenical, W. (2018). Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora. Journal of the American Chemical Society, 140(34), 10775–10784.
Patin, N. V., Floros, D. J., Hughes, C. C., Dorrestein, P. C., & Jensen, P. R. (2018). The role of inter-species interactions in Salinispora specialized metabolism. Microbiology-Sgm, 164(7), 946–955.
Bruns, H., Crusemann, M., Letzel, A. C., Alanjary, M., McInerney, J. O., Jensen, P. R., Schulz, S., Moore, B. S., & Ziemert, N. (2018). Function-related replacement of bacterial siderophore pathways. Isme Journal, 12(2), 320–329.
Amos, G. C. A., Awakawa, T., Tuttle, R. N., Letzel, A. C., Kim, M. C., Kudo, Y., Fenical, W., Moore, B. S., & Jensen, P. R. (2017). Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality. Proceedings of the National Academy of Sciences of the United States of America, 114(52), E11121–E11130.
Machado, H., Tuttle, R. N., & Jensen, P. R. (2017). Omics-based natural product discovery and the lexicon of genome mining. Current Opinion in Microbiology, 39, 136–142.
Letzel, A. C., Li, J., Amos, G. C. A., Millan-Aguinaga, N., Ginigini, J., Abdelmohsen, U. R., Gaudencio, S. P., Ziemert, N., Moore, B. S., & Jensen, P. R. (2017). Genomic insights into specialized metabolism in the marine actinomycete Salinispora. Environmental Microbiology, 19(9), 3660–3673.
Gallagher, K. A., Wanger, G., Henderson, J., Llorente, M., Hughes, C. C., & Jensen, P. R. (2017). Ecological implications of hypoxia-triggered shifts in secondary metabolism. Environmental Microbiology, 19(6), 2182–2191.
Millan-Aguinaga, N., Chavarria, K. L., Ugalde, J. A., Letzel, A. C., Rouse, G. W., & Jensen, P. R. (2017). Phylogenomic Insight into Salinispora (Bacteria, Actinobacteria) Species Designations. Scientific Reports, 7.
Asolkar, R. N., Singh, A., Jensen, P. R., Aalbersberg, W., Carte, B. K., Feussner, K. D., Subramani, R., DiPasquale, A., Rheingold, A. L., & Fenical, W. (2017). Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete Glade MAR4. Tetrahedron, 73(16), 2234–2241.
Crusemann, M., O’Neill, E. C., Larson, C. B., Melnik, A. V., Floros, D. J., da Silva, R. R., Jensen, P. R., Dorrestein, P. C., & Moore, B. S. (2017). Prioritizing natural product diversity in a collection of 146 bacterial strains based on growth and extraction protocols. Journal of Natural Products, 80(3), 588–597.
Agarwal, V., Blanton, J. M., Podell, S., Taton, A., Schorn, M. A., Busch, J., Lin, Z., Schmidt, E. W., Jensen, P. R., Paul, V. J., Biggs, J. S., Golden, J. W., Allen, E. E., & Moore, B. S. (2017). Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges. Nat Chem Biol, advance online publication.
Patin, N. V., Schorn, M., Aguinaldo, K., Lincecum, T., Moore, B. S., & Jensen, P. R. (2017). Effects of actinomycete secondary metabolites on sediment microbial communities. Applied and Environmental Microbiology, 83(4).
Schorn, M. A., Alanjary, M. M., Aguinaldo, K., Korobeynikov, A., Podell, S., Patin, N., Lincecum, T., Jensen, P. R., Ziemert, N., & Moore, B. S. (2016). Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters. Microbiology-Sgm, 162(12), 2075–2086.
Jensen, P. R. (2016). Natural products and the gene cluster revolution. Trends in Microbiology, 24(12), 968–977.
Floros, D. J., Jensen, P. R., Dorrestein, P. C., & Koyama, N. (2016). A metabolomics guided exploration of marine natural product chemical space. Metabolomics, 12(9).
Wang, M. X., Carver, J. J., Phelan, V. V., Sanchez, L. M., Garg, N., Peng, Y., Nguyen, D. D., Watrous, J., Kapono, C. A., Luzzatto-Knaan, T., Porto, C., Bouslimani, A., Melnik, A. V., Meehan, M. J., Liu, W. T., Criisemann, M., Boudreau, P. D., Esquenazi, E., Sandoval-Calderon, M., … Bandeira, N. (2016). Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology, 34(8), 828–837.
Patin, N. V., Duncan, K. R., Dorrestein, P. C., & Jensen, P. R. (2016). Competitive strategies differentiate closely related species of marine actinobacteria. Isme Journal, 10(2), 478–490.
Tang, X. Y., Li, J., Millan-Aguinaga, N., Zhang, J. J., O’Neill, E. C., Ugalde, J. A., Jensen, P. R., Mantovani, S. M., & Moore, B. S. (2015). Identification of thiotetronic acid antibiotic biosynthetic pathways by target-directed genome mining. Acs Chemical Biology, 10(12), 2841–2849.
Ruckert, C., Leipoldt, F., Zeyhle, P., Fenical, W., Jensen, P. R., Kalinowski, J., Heide, L., & Kaysser, L. (2015). Complete genome sequence of Streptomyces sp CNQ-509, a prolific producer of meroterpenoid chemistry. Journal of Biotechnology, 216, 140–141.
Gallagher, K. A., & Jensen, P. R. (2015). Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade. Bmc Genomics, 16.
Choi, E. J., Nam, S. J., Paul, L., Beatty, D., Kauffman, C. A., Jensen, P. R., & Fenical, W. (2015). Previously uncultured marine bacteria linked to novel alkaloid production. Chemistry & Biology, 22(9), 1270–1279.
Nam, S. J., Kauffman, C. A., Jensen, P. R., Moore, C. E., Rheingold, A. L., & Fenical, W. (2015). Actinobenzoquinoline and actinophenanthrolines a-c, unprecedented alkaloids from a marine actinobacterium. Organic Letters, 17(13), 3240–3243.
Duncan, K. R., Crusemann, M., Lechner, A., Sarkar, A., Li, J., Ziemert, N., Wang, M. X., Bandeira, N., Moore, B. S., Dorrestein, P. C., & Jensen, P. R. (2015). Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species. Chemistry & Biology, 22(4), 460–471.
Wietz, M., Millan-Aguinaga, N., & Jensen, P. R. (2014). CRISPR-Cas systems in the marine actinomycete Salinispora: linkages with phage defense, microdiversity and biogeography. Bmc Genomics, 15.
Ziemert, N., Lechner, A., Wietz, M., Millan-Aguinaga, N., Chavarria, K. L., & Jensen, P. R. (2014). Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora. Proceedings of the National Academy of Sciences of the United States of America, 111(12), E1130–E1139.
Jensen, P. R., Chavarria, K. L., Fenical, W., Moore, B. S., & Ziemert, N. (2014). Challenges and triumphs to genomics-based natural product discovery. Journal of Industrial Microbiology & Biotechnology, 41(2), 203–209.
Farnaes, L., Coufal, N. G., Kauffman, C. A., Rheingold, A. L., DiPasquale, A. G., Jensen, P. R., & Fenical, W. (2014). Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis. Journal of Natural Products, 77(1), 15–21.
Gallagher, K. A., Rauscher, K., Ioca, L. P., & Jensen, P. R. (2013). Phylogenetic and chemical diversity of a hybrid-isoprenoid producing streptomycete lineage. Applied and Environmental Microbiology, 79(22), 6894–6902.
Nam, S. J., Kauffman, C. A., Paul, L. A., Jensen, P. R., & Fenical, W. (2013). Actinoranone, a cytotoxic meroterpenoid of unprecedented structure from a marine adapted streptomyces sp. Organic Letters, 15(21), 5400–5403.
Freel, K. C., Millan-Aguinaga, N., & Jensen, P. R. (2013). Multilocus sequence typing reveals evidence of homologous recombination linked to antibiotic resistance in the genus salinispora. Applied and Environmental Microbiology, 79(19), 5997–6005.
Ilan, E. Z., Torres, M. R., Prudhomme, J., Le Roch, K., Jensen, P. R., & Fenical, W. (2013). Farnesides A and B, sesquiterpenoid nucleoside ethers from a marine-derived Streptomyces sp., strain CNT-372 from Fiji. Journal of Natural Products, 76(9), 1815–1818.
Wietz, M., Duncan, K., Patin, N. V., & Jensen, P. R. (2013). Antagonistic interactions mediated by marine bacteria: The role of small molecules. Journal of Chemical Ecology, 39(7), 879–891.
Prieto-Davo, A., Villarreal-Gomez, L. J., Forschner-Dancause, S., Bull, A. T., Stach, J. E. M., Smith, D. C., Rowley, D. C., & Jensen, P. R. (2013). Targeted search for actinomycetes from nearshore and deep-sea marine sediments. Fems Microbiology Ecology, 84(3), 510–518.