Castro-Falcón, G., Guillén-Matus, D. G., Silva, E. B. D., Guo, W., Ross, A., Sá Magalhães Serafim, M., Fernandes, T. H. M., Tantillo, D. J., O’Donoghue, A. J., & Jensen, P. R. (2025). Structure Elucidation, Biosynthetic Gene Cluster Distribution, and Biological Activities of Ketomemicin Analogs in Salinispora. Marine Drugs, 23(3), 126. https://doi.org/10.3390/md23030126

Beattie, G. A., Edlund, A., Esiobu, N., Gilbert, J., Nicolaisen, M. H., Jansson, J. K., Jensen, P., Keiluweit, M., Lennon, J. T., Martiny, J., Minnis, V. R., Newman, D., Peixoto, R., Schadt, C., & Van Der Meer, J. R. (2025). Soil microbiome interventions for carbon sequestration and climate mitigation. MSystems, 10(1), e01129-24. https://doi.org/10.1128/msystems.01129-24

Sweeney, D., Bogdanov, A., Chase, A. B., Castro-Falcón, G., Trinidad-Javier, A., Dahesh, S., Nizet, V., & Jensen, P. R. (2024). Pattern-Based Genome Mining Guides Discovery of the Antibiotic Indanopyrrole A from a Marine Streptomycete. Journal of Natural Products, acs.jnatprod.4c00934. https://doi.org/10.1021/acs.jnatprod.4c00934

Bogdanov, A., Salib, M. N., Chase, A. B., Hammerlindl, H., Muskat, M. N., Luedtke, S., Da Silva, E. B., O’Donoghue, A. J., Wu, L. F., Altschuler, S. J., Molinski, T. F., & Jensen, P. R. (2024). Small molecule in situ resin capture provides a compound first approach to natural product discovery. Nature Communications, 15(1), 5230. https://doi.org/10.1038/s41467-024-49367-x

Stack, M. E., Richardot, W. H., Garcia, R., Nguyen, T., Choy, C. A., Jensen, P. R., Gutleben, J., Dodder, N. G., Aluwihare, L. I., & Hoh, E. (2024). Identification of DDT+ in Deep Ocean Sediment and Biota in the Southern California Bight. Environmental Science & Technology Letters, 11(5), 479–484. https://doi.org/10.1021/acs.estlett.4c00115

Sweeney, D., Chase, A. B., Bogdanov, A., & Jensen, P. R. (2024). MAR4 Streptomyces : A Unique Resource for Natural Product Discovery. Journal of Natural Products, 87(2), 439–452. https://doi.org/10.1021/acs.jnatprod.3c01007

Singh, H. W., Creamer, K. E., Chase, A. B., Klau, L. J., Podell, S., & Jensen, P. R. (2023). Metagenomic data reveals type I polyketide synthase distributions across biomes. MSystems, 8(3), e00012-23. https://doi.org/10.1128/msystems.00012-23

Chase, A. B., Bogdanov, A., Demko, A. M., & Jensen, P. R. (2023). Biogeographic patterns of biosynthetic potential and specialized metabolites in marine sediments. The ISME Journal, 17(7), 976–983. https://doi.org/10.1038/s41396-023-01410-3

Mascuch, S. J., Demko, A., Viulu, S., Ginigini, J., Soapi, K., Jensen, P., & Kubanek, J. (2022). Antibiotic activity altered by competitive interactions between two coral reef-associated bacteria. Microbial Ecology, 10. https://doi.org/10.1007/s00248-022-02016-6

Tuttle, R. N., Rouse, G. W., Castro-Falcon, G., Hughes, C. C., & Jensen, P. R. (2022). Specialized metabolite-mediated predation defense in the marine actinobacterium Salinispora. Applied and Environmental Microbiology, 88(1), 11. https://doi.org/10.1128/aem.01176-21

Klau, L. J., Podell, S., Creamer, K. E., Demko, A. M., Singh, H. W., Allen, E. E., Moore, B. S., Ziemert, N., Letzel, A. C., & Jensen, P. R. (2022). The Natural Product Domain Seeker version 2 (NaPDoS2) webtool relates ketosynthase phylogeny to biosynthetic function. Journal of Biological Chemistry, 298(10), 102480. https://doi.org/10.1016/j.jbc.2022.102480

Castro-Falcon, G., Creamer, K. E., Chase, A. B., Kim, M. C., Sweeney, D., Glukhov, E., Fenical, W., & Jensen, P. R. (2022). Structure and candidate biosynthetic gene cluster of a manumycin-type metabolite from Salinispora pacifica. Journal of Natural Products, 85(4), 980–986. ://WOS:000791431400023

Chase, A. B., Sweeney, D., Muskat, M. N., Guillen-Matus, D. G., & Jensen, P. R. (2021). Vertical Inheritance Facilitates Interspecies Diversification in Biosynthetic Gene Clusters and Specialized Metabolites. Mbio, 12(6), 15.

Demko, A. M., Patin, N. V., & Jensen, P. R. (2021). Microbial diversity in tropical marine sediments assessed using culture-dependent and culture-independent techniques. Environmental Microbiology, 17. https://doi.org/10.1111/1462-2920.15798

Shang, Z., Ferris, Z. E., Sweeney, D., Chase, A. B., Yuan, C. H., Hui, Y., Hou, L. K., Older, E. A., Xue, D., Tang, X. Y., Zhang, W. P., Nagarkatti, P., Nagarkatti, M., Testerman, T. L., Jensen, P. R., & Li, J. (2021). Grincamycins P-T: Rearranged angucyclines from the marine sediment-derived Streptomyces sp. CNZ-748 inhibit cell lines of the rare cancer pseudomyxoma peritonei. Journal of Natural Products, 84(5), 1638–1648. https://doi.org/10.1021/acs.jnatprod.1c00179

Schorn, M. A., Verhoeven, S., Ridder, L., Huber, F., Acharya, D. D., Aksenov, A. A., Aleti, G., Moghaddam, J. A., Aron, A. T., Aziz, S., Bauermeister, A., Bauman, K. D., Baunach, M., Beemelmanns, C., Beman, J. M., Berlanga-Clavero, M. V., Blacutt, A. A., Bode, H. B., Boullie, A., … van der Hooft, J. J. J. (2021). A community resource for paired genomic and metabolomic data mining. Nature Chemical Biology. https://doi.org/10.1038/s41589-020-00724-z

Kudo, Y., Awakawa, T., Du, Y. L., Jordan, P. A., Creamer, K. E., Jensen, P. R., Linington, R. G., Ryan, K. S., & Moore, B. S. (2020). Expansion of gamma-butyrolactone signaling molecule biosynthesis to phosphotriester natural products. Acs Chemical Biology, 15(12), 3253–3261. https://doi.org/10.1021/acschembio.0c00824

Roman-Ponce, B., Millan-Aguinaga, N., Guillen-Matus, D., Chase, A. B., Ginigini, J. G. M., Soapi, K., Feussner, K. D., Jensen, P. R., & Trujillo, M. E. (2020). Six novel species of the obligate marine actinobacterium Salinispora, Salinispora cortesiana sp. nov., Salinispora fenicalii sp. nov., Salinispora goodfellowii sp. nov., Salinispora mooreana sp. nov., Salinispora oceanensis sp. nov. and Salinispora vitiensis sp. nov., and emended description of the genus Salinispora. International Journal of Systematic and Evolutionary Microbiology, 70(8), 4668–4682. https://doi.org/10.1099/ijsem.0.004330

Nair, V., Kim, M. C., Golen, J. A., Rheingold, A. L., Castro, G. A., Jensen, P. R., & Fenical, W. (2020). Verrucosamide, a cytotoxic 1,4-thiazepane-containing thiodepsipeptide from a marine-derived actinomycete. Marine Drugs, 18(11). https://doi.org/10.3390/md18110549

Schlawis, C., Harig, T., Ehlers, S., Guillen-Matus, D. G., Creamer, K. E., Jensen, P. R., & Schulz, S. (2020). Extending the salinilactone family. Chembiochem, 21(11), 1629–1632. https://doi.org/10.1002/cbic.201900764

Busch, J., Agarwal, V., Schorn, M., Machado, H., Moore, B. S., Rouse, G. W., Gram, L., & Jensen, P. R. (2019). Diversity and distribution of the bmp gene cluster and its Polybrominated products in the genus Pseudoalteromonas. Environmental Microbiology, 21(5), 1575–1585. https://doi.org/10.1111/1462-2920.14532

Tuttle, R. N., Demko, A. M., Patin, N. V., Kapono, C. A., Donia, M. S., Dorrestein, P., & Jensen, P. R. (2019). Detection of natural products and their producers in ocean sediments. Applied and Environmental Microbiology, 85(8). https://doi.org/10.1128/aem.02830-18

Castro-Falcon, G., Millan-Aguinaga, N., Roullier, C., Jensen, P. R., & Hughes, C. C. (2018). Nitrosopyridine probe to detect polyketide natural products with conjugated alkenes: Discovery of novodaryamide and nocarditriene. Acs Chemical Biology, 13(11), 3097–3106. https://doi.org/10.1021/acschembio.8b00598

Kim, M. C., Machado, H., Jang, K. H., Trzoss, L., Jensen, P. R., & Fenical, W. (2018). Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora. Journal of the American Chemical Society, 140(34), 10775–10784. https://doi.org/10.1021/jacs.8b04848

Patin, N. V., Floros, D. J., Hughes, C. C., Dorrestein, P. C., & Jensen, P. R. (2018). The role of inter-species interactions in Salinispora specialized metabolism. Microbiology-Sgm, 164(7), 946–955. https://doi.org/10.1099/mic.0.000679

Bruns, H., Crusemann, M., Letzel, A. C., Alanjary, M., McInerney, J. O., Jensen, P. R., Schulz, S., Moore, B. S., & Ziemert, N. (2018). Function-related replacement of bacterial siderophore pathways. Isme Journal, 12(2), 320–329. https://doi.org/10.1038/ismej.2017.137

Amos, G. C. A., Awakawa, T., Tuttle, R. N., Letzel, A. C., Kim, M. C., Kudo, Y., Fenical, W., Moore, B. S., & Jensen, P. R. (2017). Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality. Proceedings of the National Academy of Sciences of the United States of America, 114(52), E11121–E11130. https://doi.org/10.1073/pnas.1714381115

Machado, H., Tuttle, R. N., & Jensen, P. R. (2017). Omics-based natural product discovery and the lexicon of genome mining. Current Opinion in Microbiology, 39, 136–142. https://doi.org/10.1016/j.mib.2017.10.025

Letzel, A. C., Li, J., Amos, G. C. A., Millan-Aguinaga, N., Ginigini, J., Abdelmohsen, U. R., Gaudencio, S. P., Ziemert, N., Moore, B. S., & Jensen, P. R. (2017). Genomic insights into specialized metabolism in the marine actinomycete Salinispora. Environmental Microbiology, 19(9), 3660–3673. https://doi.org/10.1111/1462-2920.13867

Gallagher, K. A., Wanger, G., Henderson, J., Llorente, M., Hughes, C. C., & Jensen, P. R. (2017). Ecological implications of hypoxia-triggered shifts in secondary metabolism. Environmental Microbiology, 19(6), 2182–2191. https://doi.org/10.1111/1462-2920.13700

Millan-Aguinaga, N., Chavarria, K. L., Ugalde, J. A., Letzel, A. C., Rouse, G. W., & Jensen, P. R. (2017). Phylogenomic Insight into Salinispora (Bacteria, Actinobacteria) Species Designations. Scientific Reports, 7. https://doi.org/10.1038/s41598-017-02845-3

Asolkar, R. N., Singh, A., Jensen, P. R., Aalbersberg, W., Carte, B. K., Feussner, K. D., Subramani, R., DiPasquale, A., Rheingold, A. L., & Fenical, W. (2017). Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete Glade MAR4. Tetrahedron, 73(16), 2234–2241. https://doi.org/10.1016/j.tet.2017.03.003

Crusemann, M., O’Neill, E. C., Larson, C. B., Melnik, A. V., Floros, D. J., da Silva, R. R., Jensen, P. R., Dorrestein, P. C., & Moore, B. S. (2017). Prioritizing natural product diversity in a collection of 146 bacterial strains based on growth and extraction protocols. Journal of Natural Products, 80(3), 588–597. https://doi.org/10.1021/acsjnatprod.6b00722

Agarwal, V., Blanton, J. M., Podell, S., Taton, A., Schorn, M. A., Busch, J., Lin, Z., Schmidt, E. W., Jensen, P. R., Paul, V. J., Biggs, J. S., Golden, J. W., Allen, E. E., & Moore, B. S. (2017). Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges. Nat Chem Biol, advance online publication. https://doi.org/10.1038/nchembio.2330

Patin, N. V., Schorn, M., Aguinaldo, K., Lincecum, T., Moore, B. S., & Jensen, P. R. (2017). Effects of actinomycete secondary metabolites on sediment microbial communities. Applied and Environmental Microbiology, 83(4). https://doi.org/10.1128/aem.02676-16

Schorn, M. A., Alanjary, M. M., Aguinaldo, K., Korobeynikov, A., Podell, S., Patin, N., Lincecum, T., Jensen, P. R., Ziemert, N., & Moore, B. S. (2016). Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters. Microbiology-Sgm, 162(12), 2075–2086. https://doi.org/10.1099/mic.0.000386

Jensen, P. R. (2016). Natural products and the gene cluster revolution. Trends in Microbiology, 24(12), 968–977. https://doi.org/10.1016/j.tim.2016.07.006

Floros, D. J., Jensen, P. R., Dorrestein, P. C., & Koyama, N. (2016). A metabolomics guided exploration of marine natural product chemical space. Metabolomics, 12(9). https://doi.org/10.1007/s11306-016-1087-5

Wang, M. X., Carver, J. J., Phelan, V. V., Sanchez, L. M., Garg, N., Peng, Y., Nguyen, D. D., Watrous, J., Kapono, C. A., Luzzatto-Knaan, T., Porto, C., Bouslimani, A., Melnik, A. V., Meehan, M. J., Liu, W. T., Criisemann, M., Boudreau, P. D., Esquenazi, E., Sandoval-Calderon, M., … Bandeira, N. (2016). Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology, 34(8), 828–837. https://doi.org/10.1038/nbt.3597

Patin, N. V., Duncan, K. R., Dorrestein, P. C., & Jensen, P. R. (2016). Competitive strategies differentiate closely related species of marine actinobacteria. Isme Journal, 10(2), 478–490. https://doi.org/10.1038/ismej.2015.128

Tang, X. Y., Li, J., Millan-Aguinaga, N., Zhang, J. J., O’Neill, E. C., Ugalde, J. A., Jensen, P. R., Mantovani, S. M., & Moore, B. S. (2015). Identification of thiotetronic acid antibiotic biosynthetic pathways by target-directed genome mining. Acs Chemical Biology, 10(12), 2841–2849. https://doi.org/10.1021/acschembio.5b00658

Ruckert, C., Leipoldt, F., Zeyhle, P., Fenical, W., Jensen, P. R., Kalinowski, J., Heide, L., & Kaysser, L. (2015). Complete genome sequence of Streptomyces sp CNQ-509, a prolific producer of meroterpenoid chemistry. Journal of Biotechnology, 216, 140–141. https://doi.org/10.1016/j.jbiotec.2015.08.009

Gallagher, K. A., & Jensen, P. R. (2015). Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade. Bmc Genomics, 16. https://doi.org/10.1186/s12864-015-2110-3

Choi, E. J., Nam, S. J., Paul, L., Beatty, D., Kauffman, C. A., Jensen, P. R., & Fenical, W. (2015). Previously uncultured marine bacteria linked to novel alkaloid production. Chemistry & Biology, 22(9), 1270–1279. https://doi.org/10.1016/j.chembiol.2015.07.014

Nam, S. J., Kauffman, C. A., Jensen, P. R., Moore, C. E., Rheingold, A. L., & Fenical, W. (2015). Actinobenzoquinoline and actinophenanthrolines a-c, unprecedented alkaloids from a marine actinobacterium. Organic Letters, 17(13), 3240–3243. https://doi.org/10.1021/acs.orglett.5b01387

Duncan, K. R., Crusemann, M., Lechner, A., Sarkar, A., Li, J., Ziemert, N., Wang, M. X., Bandeira, N., Moore, B. S., Dorrestein, P. C., & Jensen, P. R. (2015). Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species. Chemistry & Biology, 22(4), 460–471. https://doi.org/10.1016/j.chembiol.2015.03.010

Wietz, M., Millan-Aguinaga, N., & Jensen, P. R. (2014). CRISPR-Cas systems in the marine actinomycete Salinispora: linkages with phage defense, microdiversity and biogeography. Bmc Genomics, 15. https://doi.org/10.1186/1471-2164-15-936

Ziemert, N., Lechner, A., Wietz, M., Millan-Aguinaga, N., Chavarria, K. L., & Jensen, P. R. (2014). Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora. Proceedings of the National Academy of Sciences of the United States of America, 111(12), E1130–E1139. https://doi.org/10.1073/pnas.1324161111

Jensen, P. R., Chavarria, K. L., Fenical, W., Moore, B. S., & Ziemert, N. (2014). Challenges and triumphs to genomics-based natural product discovery. Journal of Industrial Microbiology & Biotechnology, 41(2), 203–209. https://doi.org/10.1007/s10295-013-1353-8

Farnaes, L., Coufal, N. G., Kauffman, C. A., Rheingold, A. L., DiPasquale, A. G., Jensen, P. R., & Fenical, W. (2014). Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis. Journal of Natural Products, 77(1), 15–21. https://doi.org/10.1021/np400466j